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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51fe81860149f75f8e9d3d0961e682a8bc4e414edf453b773e379f39c1dcf5c9' 
  AND token = '+Nzi4SY6OMUvds1q18owYKywFVHuwwhsg9NIaQRhSi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}