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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ff1e5a228a681accec70b4dac01cb6ebb674cc8682367fde0a6de6a5db384b' 
  AND token = 'JXopyvLqePcJAi+qIddyC7WzdrMYnAVNqlY95IOfxEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}