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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c22c96b369230a9efc5e40e2b79b61dfe20fb633c19d4cba69db5ddea1ff9c90' 
  AND token = 'mi89eb8WAOnzcDp//L9hJmDgsqvecwyKm/XYy5XRgfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}