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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a75d54c4ce1f493abf321c0421add4e8fff6811b5852f8eef71b665306e248' 
  AND token = 'WKQlX0WE37GDXztjqUP9nt/aWGdh9XQqzSpo8M903NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}