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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ba6a80e90b260cb285421f315acdfeda14b9d75badc91ae91f2cabe2d120c0' 
  AND token = 'BOX+RF0vZ/M0goMZKw2yrb8d1x4hG/FQXocUWepw2GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}