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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0bdedb185882dce3886b7684a2114e2e6ebbfbcb6199b9e160f74fe98384ab7' 
  AND token = 'ThmRHG/M1LMDt6xrGI++Mp516Ov5KgY1QWUyloS6xNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}