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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58860adc11168a4a761a6ba34dfc91bb1dbdfb0413f89b2b781e10a779781e12' 
  AND token = 'BtjxDt7oSPcOJm/FCcpcX/CqAyrHBy3CHnQAWBlC8Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}