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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3351d6176e60300214339f16eb4d72a9b2f7861f4179a6beddd640a4ef65f087' 
  AND token = 'EBu53Gjj2koY20lmVQecYqxDGbEnynZX9x91FbaU2LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}