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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adfa4e8abb9d26e767d4cb4b588c6d8a45087e913e3411ede986a448d03dbd1c' 
  AND token = 'T6wsTm6JdTRn6dg8EMzkcqn9Z6qFEDADfvKTYDFb5bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}