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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e01d3a4f91097ab02b82a521336a30a7535c0978ab20a2af098f11f03bafe075' 
  AND token = 'e0bUN4j4ftFzR5hOTTaJ2exxHNXLCA71IwaXREmS3CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}