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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6adc21b470172e54aa36f979757e0a678457aa223553778a35169f82a06d1300' 
  AND token = 'BxuZg8ycemgrp0yRvR8K/fg4Rq9sQetL9IKTW+Si3Co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}