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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43219b3300404cbc3e074e9ae4dce9971a0496de3473762ed9775db3edc117c9' 
  AND token = 'v28Ob6/yfDxU9CUn8gkVzhFqDxF4PBbChNtt51rH61E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}