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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '329336bab61375f132e0fbf1574c049c47c41f9e33b9ede1e0ed9f8b5bf23d96' 
  AND token = 'H81KCFEIO5jbs2GVmLIxWONjIAmx7Yq/zoRonDtH7AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}