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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78198e0f9c97e8f88b99cd210139df865350c7250a4c5485e13abde96a62d4d7' 
  AND token = '9ti/UV7FnBZ6DA4Vn0iMJ2XFeKJrVpH1eMownz1V2NM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}