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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef235ea49180121ebe3f1df8785c209841cd40b31d41513adc9f6124a2532d3' 
  AND token = 'HaFsP6OsFvig9zuNIQtQ2up7XYtCl6uQTDM/CWUS8o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}