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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e840a571a197489b96216b97665ef13ddd406fdef99d10a5e07ee1d6603e9db4' 
  AND token = 'b/h38HEfdx/5UdHcs1pitfS+EJ40Dri0+CcCaCiMSsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}