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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a4654b20ab6e5f5a4225fcf2103b89be507b0b626aff8a4335a2e9350198af2' 
  AND token = '1MrF1cFHuGekioDxrQFJXMDeyrnwvZCCmyb8oXHQGe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}