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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c3d2f7cd96306d76237d0718fdb8b44136cc173549208318cedb3cc77ba1e9' 
  AND token = 'y7wjG/pwDn9eiz2FteZhU0LRNTiXrLqdnQ5wFqrIPKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}