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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef634f5117fd9d71c243c11d0f36e105409bc51f750a235185f4855a1b6e3af2' 
  AND token = 'gECxVNVN2loIwP6UPZxI0suM7QNmUywPEdeeNcrszUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}