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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a57d4ffb49e9760260b44ed6d79db448d06a9fc6d87554d9fb8909fb3a7e69' 
  AND token = 'n7WD6+MDKFAq/2DCcd0f6DXo9HKm1rXtTciSwGE5K3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}