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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6cecbb7aced5268b5ad43bb5d33d2e67e0052e47397758f2b6c8e4906b2e0fe' 
  AND token = 'IzHcDRsGhihPdQFUQjqYXSaEj0kN6zOy5uo4FyiHI+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}