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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd63073802431bdb2756b1d4601f510dafc053bd7f7b06e44439a17c73e1e11' 
  AND token = 'GbYlzV06Yag53PRIj8XkJEaF3S0RTrvWRKfwzAN4kmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}