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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d027dc7cb70917d3b31f3d4b3681e9242a2bb38a38b3c8d0c2b3048221d27f3' 
  AND token = 'BlVkBSSIXAaCt9uqauEtjAtpXb7N04UbiKUkeMVjkf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}