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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be6abb5c0b88141e96b7744d3cc289479d2bd684a7edc1fdeaa54dae21fe17d2' 
  AND token = 'NRs29wzN7XmoElaPgZ2hd79FiEOw88y4hfdIQr57W48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}