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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0bd6c0074a8f6d920ff19946e7fd97e7fec107e5ce6d7deb1d274992d095734' 
  AND token = 'a6N7yHb4gUgmRKMzCJ5PBmJyDpBhubRyWS+dHwL34MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}