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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7881ec1893e4c05bc921ab5fb40cab05c80febe1e5d90c07a0bb3ecefe7d1f36' 
  AND token = 'SKxno7FGcc5qQveOEx5iXAfw1fRgsSRufGpJCDnufn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}