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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2405cc4922597d3518941f7eab2bb595b030f084a65b961812d3466a5ccb94f3' 
  AND token = '4A4r7B1hTiDi8e5hcy3BmawMQn2VgKxL/7zHjGDxM8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}