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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a4228cd23aa2db2ac9a283fbf19760ec26116e825fc789f9f6831ad1a70437e' 
  AND token = 'hNkJ3wLgX/6JEC3z1q/hIcKZx9aOkHV7j87o0qK1yS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}