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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25850078df362974e673e001713012b0d288bdb77754d3eeae1361aa6fd5b1fe' 
  AND token = 'mnW6eOxLYBv4IJzb21Hgj6GAS4E+94vIPxVM4hKS90o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}