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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a3168ed31f5f68ca121a7311312180adb1d5a5afc9a41b75e6a8af8772ca011' 
  AND token = 'Z4wiDCUkGseH8zp9X+HZ3oF2B0p359MSUbGtOSbLECM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}