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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4488cfff86cbaa955ce8370c6f26e7d8ecc554b7151cb03ffe44f29b36e5d7' 
  AND token = 'PRbwq/Nk99t0Vlqsok7j0V9RHKGRykig4Jwl5+1Xjho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}