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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b823db774a235397b09ef1ccc0672b33ca38ab5d179ff6f8b590ac8179e89c3' 
  AND token = 'uV4nxzgsdufaI2901tz5y9GoVtRGRt10P2W072HdGhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}