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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27721ca7928c845e7456f111dd4540d2fe264944442a8c0cc866c7cb5f4c8551' 
  AND token = 'tlInOW6UPPS/Q1i8E4LoRvaEDlvqeXq8B39iRe4r1q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}