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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b67a3ffeffe52b6e35910160578e8aa94c2793a862641e9049fb9e766c22299a' 
  AND token = 'UkWHS9CvOmBcLrhnCsVTp5Hu5crLZsxyQNbsfg2B9DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}