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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac48a178ced4e3b83e7b509ce8e34ef823fcaddb8c4906874161fd859d63c367' 
  AND token = 'njVXWu7QKh+3lFxe1K0kN6nZtGkJE+2V4WZZvKrhV1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}