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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b60ffb34d85ff85db2c0ee7a1df609b75811c7aa95ece64c25aadce6486c7f61' 
  AND token = 'tithKVQ11k2PdWcTI/eURiVDWPcB3ZhLH9y/PmVxihY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}