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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c99c94403aca6f808a864260bcdd4d6e7878b3ff5364245ba31c19e46e570f1' 
  AND token = 'pE7ihMhOYMazczI5b6fRRr4lVE9p3BDRYsN8s63Tss0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}