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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82cf1bd37454618f298ecbc10137e329341c3ed553dfc164fc8b264158c27838' 
  AND token = 'Q8o2e3Bm8V6qXrUF10WZnIAtvJIcf5p6EsfhED1/r8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}