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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66689ef38ffa5a4df87706f22c0820063aabcc468a6ee97f490f6d7a7eb5f3b8' 
  AND token = 'D56NEup71znaKabOmZUWYQdT/jXdzRzrup5meTWC1uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}