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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4082c1efdf9f6b1b177c3c6999b2c5f8517e0199a4003c5c4170b22ac79f255c' 
  AND token = 'eG5Rtqt8b2p0ejBu3B8cKJQIbriKkgMSUD7kAiU5Mog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}