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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c372db1ec49e7ed0049ac3a8f67d46fff8dedb493f4961772b26358709cbf9' 
  AND token = 'yb/NL+hs9/KtSLEUgaqrB3K+6K4a41VqgSrgp3B3SYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}