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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56656d6f67d4d4237fa2097a7f4fcb148733e8611f3c2cd19f9c268662681198' 
  AND token = 'H/JXYPWdL1lorp30djiXxZ3ho7DMDCrQjFbFxYWAVn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}