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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6886ab5524325b810fdb2e2d4351b54297f9a5e6253a82e3db389d54199edbff' 
  AND token = 'dD84xjjVRsQi5Ik+3LwVQ6jfzjIgn0QgxPUeANYD9Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}