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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e778e949be4fb3d5b30a37315fc1a1db6698f9b7cb7c0c095ebf44c1934752' 
  AND token = 'Agwb/6S8Er/rYFGbbEcERdafqfLgVYFipZyihVrJnsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}