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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ac1750f9d7b5b4252ccca7aa494e9a17468f5848a8c33a23443bf07f6d17b01' 
  AND token = 'IXES9j8RmdBRSRzat3ljl4Ns7AMWS63hFovnonJhv6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}