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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cb65d948b533a8b12689b9fcb7395fe8e799076bdfc3e003c81bed6b6bcd7ec' 
  AND token = '/hSy+ZxUM4Yo+g+wR+DhyN1UybiN+H8AY8+fk75dw+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}