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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '914ad5e47b8b650022f7e458e3c1603711d6afca3be6cd55bc9211cbe44914a9' 
  AND token = 'ua1xnf/hqyFSmx3K+cAWBOawWYWTc9z2CUHEtIdWaCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}