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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e176886697f597d9fb6fec2da406b0a9bacda094d632bed4397777eb23eda3' 
  AND token = '+7EfSrcXAg8gM5ERicE32aSyPx3ZrEoJDJzj4ltmNIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}