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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b037d44108e91ba1e11323381e7dfda81d2c5df111d4d5c81be90821300676' 
  AND token = 'tz5fvU2d9Lftw5hMSFXNrJMYzlUsCznqDNql7AdYiOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}