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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '731b7cd6faf45444936e49fb4a7822d8f58671d9a979b1a7eddf64507439bba3' 
  AND token = '6lDlQpyTtuTC6xQ1vBer3PGgPQjLSRmhsEWy2QY9xy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}